Abstract: End-Stage Dementia and Entropy Definition of Suffering.

Objectives: A new definition of human suffering and satisfaction according to the entropy hypothesis may facilitate
comprehension of health, disease and the aging process.

Methods: A cohort study of 71 patients (28 females, 43 males), with very advanced dementia, who died in our ward during the study period. The intense suffering level of end-stage dementia patients was evaluated by the (MSSE) scale.

Results: Suffering level in end-stage dementia has a significant correlation with short survival, advancing age, more severe illness, malnutrition, the existence of decubitus ulcers, and the administration of medications. Established correlations could be explained by the enhanced level of the patients’ body entropy.

Discussion: Suffering and satisfaction are functional levels of human entropy.
An elevated level of human entropy is a measure of disorder, a process of aging and torment of the patient.

Keywords: Dementia, suffering, entropy, disease, aging.